Iranian supreme leader Ali Khamenei mocked President Joe Biden as a "poor, demented" man and led a crowd in chants of "death to America" during a speech on state television on Saturday. Biden turned 80 on Sunday, and his age and declining mental sharpness have been a matter of public speculation since his election in 2020. Khamenei's comments come as the Biden administration said this week it is still interested in reaching a nuclear deal with Iran, despite a reported stalemate in the negotiations and the Iranian government's ongoing violent crackdown on nationwide anti-government protests. In Khamenei's speech, which was translated by the Middle East Media Research Institute, the Iranian leader claimed that the Islamic Republic's "advancement" was "intolerable and unbearable for the West." He criticized U.S. presidents since the 1979 Iranian revolution, singling out Donald Trump as a "dope" and Biden as "demented.